Tamatama Otome: Shounen ga Shoujo ni Naru Toki

Yuri is dissatisfied with her childhood friend Taku, finding him lacking in masculinity. She hopes to deepen their relationship, but Taku is unable to take any decisive or romantic steps. One day, a demon interrupts them and shares a prophecy about Taku's future descendant saving the world. After finishing, the demon curses Taku’s testicles to prevent the prophecy from happening. The curse unexpectedly makes Taku even more feminine. Yuri worries that her hopes for a romantic future with Taku may be ruined, but wonders if she can help him reclaim his masculinity.