Tập 2: Hyakkimaru tiết lộ quá khứ của mình cho Dororo trong khi tìm cách trả thù các ác ma và samurai.

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Dororo insists on following Hyakkimaru, so he tells Dororo how Jukai-sensei found him as an infant Hyakkimaru on the riverbank and took him home and how the doctor made prostheses for him so that he appeared normal. However Hyakkimaru learned that only by defeating the 48 demons who possessed his body parts could he become fully human. To help Hyakkimaru in his quest, Jukai-sensei inserted an excellent sword he received from a general into Hyakkimaru's prosthic arm. On his travels Hyakkimaru met an old blind monk named Zatou (座頭) who realized Hyakkimaru's sad predicament. He took Hyakkimaru to an orphanage of children damaged by war where Hyakkimaru stayed and honed his fighting skills. There he met and fell in love with Mio, but one day the orphanage was set on fire by the local samurai with Mio and the children inside, his dreams vanishing in the flames. Enraged, Hyakkimaru attacked and killed all the samurai. (Source: Wikipedia)