Ep. 492: Koshi reveals Rena's blood type AB while Eisuke denies being her brother due to his own type O status.

Koshi confirms the photograph depicts Rena and shows a news clip stating her blood type is AB. Eisuke rejects the idea that Rena is his sister, explaining that he received a blood transfusion from her and has type O blood, which cannot receive type AB. Conan suspects Eisuke has hidden motives for seeking Rena. The following day, Eisuke invites Ran and Sonoko to his former mansion to retrieve his mother's belongings. Kogoro is also present, hired to investigate a murder at the estate that happened a year prior. Inside, Eisuke finds his birth certificate, verifying his type O status. Meanwhile, Kogoro speaks with the mansion owner, Kakuzo Okudaira, about the death of his son, Tango Okudaira. Kakuzo tells Kogoro that he suspects the killer is one of three people currently residing in the mansion.
Episodes
- Ep. 488 · Detective Boys visit a TV studio and encounter a murdered director while suspecting a rock vocalist.
- Ep. 489 · Eri defends Hiroaki while evidence points to Mariko, leading to Hiroaki's fatal fall and Reiko's resignation.
- Ep. 490 · Heiji Reminisces About a Superior Detective While Investigating a Ski Resort Murder
- Ep. 491 · Conan investigates Eisuke's search for his missing sister who resembles Rena Mizunashi
- Ep. 492 · Koshi reveals Rena's blood type AB while Eisuke denies being her brother due to his own type O status.
- Ep. 493 · Kakuzo reveals murder details and is found hanged after a blackout.
- Ep. 494 · Conan uncovers the method behind the murders of Kakuzo and Tango
- Ep. 495 · Conan and FBI investigate Haido Central Hospital for Black Organization member
- Ep. 496 · Nurse reveals Eisuke's leukemia surgery, suggesting he and Rena are siblings