Ep. 16: Lupin battles Transformation Sickness that turns him into a cruel criminal at midnight
Aired on January 23, 1978

Lupin suffers from Transformation Sickness, a condition that turns him into a cruel, cold-blooded criminal at midnight. He loses all memory of his actions by morning. Despairing over these events, he considers suicide. The narrative questions whether this alternate persona is truly him. The story explores his psychological struggle with the illness and the identity crisis it causes. Lupin faces the horror of his midnight actions and the confusion of his morning amnesia. The episode examines the nature of his character and the impact of the sickness on his life.
Episodes
- Ep. 12 · Lupin Gang Targets Napoleon-Era Bordeaux Gifted to US President
- Ep. 13 · Lupin pursues Zenigata to retrieve microfilm hidden in his molar while the inspector suffers hallucinations.
- Ep. 14 · Lupin must return a cursed ruby to a Caribbean cult to save Fujiko from a mysterious fever.
- Ep. 15 · Lupin faces a gem theft challenge aboard the Hendenburg airship
- Ep. 16 · Lupin battles Transformation Sickness that turns him into a cruel criminal at midnight
- Ep. 17 · Lupin III confronts human bomb threats in a blackmail scheme targeting an Arab nation's oil fields.
- Ep. 18 · Lupin hides the Black Panther emerald in a museum while rival inspectors investigate its disappearance.
- Ep. 19 · Lupin faces a keyless safe challenge from the bankrupt Marukin Safe Company's son.
- Ep. 20 · Lupin steals General Hatler's toupee while attempting to take his ruby medallion.