

Black Jack 21
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Episodes (17)
1EP 1Black Jack Regains License After Treating Detective's Son with Paget's Disease
Apr 10, 2006Black Jack treats Detective Takasugi’s son, who suffers from Paget's Disease, to regain his medical license. He refuses bureaucratic registration and is arrested for practicing without one. While imprisoned, Italian billionaire Mr. Boccherini begs him to save his grandson. The Japan Medical Association head denies release despite bribery. Dr. White performs the surgery using robotic aids. Boccherini reports a miraculous recovery, but Black Jack suspects the outcome is too radical. The boy subsequently dies. Enraged, the billionaire arranges for the medical association head’s son to be shot. The father pleads with Black Jack to save the boy. Black Jack agrees to perform the operation, but demands an outrageous sum of money for his services.
2EP 2Black Jack Reconnects With His Father After Two Decades
Apr 17, 2006Black Jack, who harbors resentment toward his father for abandoning him and his mother Mio after an explosion, finally responds to a call from Kagemitsu Hazama after 21 years. Kagemitsu proposes a financial partnership and requests plastic surgery on his second wife, Renka, who suffered burns in a fire, instructing Jack to make her the most beautiful woman alive. Upon removing the bandages, Kagemitsu is shocked to see Renka resembles his deceased wife, Mio. Later, Black Jack faces an assassination attempt by a mysterious organization and is caught in a massive explosion upon returning home.
3EP 3Pinoko refuses to accept Black Jack's death while he hides from assassins
Apr 24, 2006Pinoko refuses to believe Black Jack is dead, digging through their bombed house rubble. She stays at Tetsu’s diner before reluctantly joining a hospital family. Black Jack survived the blast by Benitokage, aided by Toriton and fishermen. He hides to protect Pinoko and friends, suspecting the bomb resembles one from 21 years ago. Investigating, he finds a photo in Dr. Honma’s old clinic with Honma, Kreutuzer, and his father. After Pinoko locates him, Jack emerges from hiding to pursue the assassins.
4EP 4Black Jack and Pinoko travel to Europe to find Dr Kreutzer and uncover secrets from a photograph.
May 8, 2006Black Jack and Pinoko fly to Europe to track down Dr Kreutzer, a man recognized from a photograph found at Honma's clinic. While visiting a hospital run by him, Jack befriends a girl named Suzie. He discovers Dr Kreutzer has been in a persistent vegetative state for two months following a car accident. Hospital controller Mr Devon asks Jack to impersonate the doctor and operate on a cancer patient. Jack initially refuses but accepts the high fee after Pinoko reveals the patient is Suzie's mother. After the surgery, Dr Stein, who was in the old photograph, mentions the organization and the Noir Project.
5EP 5Black Jack visits Dr. Stein in Germany to investigate an experimental robotic arm procedure for a young pianist.
May 15, 2006Black Jack travels to Germany to find Dr. Stein, a renowned specialist in prosthetics and transplants, after meeting him at Kreutzer's hospital. There, he meets Dr. Konomi Kuwata, who reveals Stein plans to attach an experimental robotic arm to Triton, a pianist suffering from Ewing's sarcoma. Triton prefers to retain his natural arm and master music through difficult practice. Jack secures Dr. Kuwata's help to save the boy's arm, refusing Stein's experimental approach. Following this intervention, Jack intends to pursue Stein to England. Meanwhile, Benitokage and the organization's assassins continue their relentless pursuit of Jack, maintaining pressure on him as he navigates these complex medical and personal decisions.
6EP 6Black Jack rides a hijacked airborne clinic to England while performing emergency surgery.
May 22, 2006Black Jack travels to England aboard Dr. White’s Sky Hospital, an aircraft converted into a mobile clinic, accompanied by Dr. Ayako Nishikawa. Militants from Taranistan hijack the plane to repurpose it for combat, injuring the pilots with a stun grenade. Black Jack performs critical surgery under extreme conditions to save the crew, while Dr. White battles to maintain control of the fuel-depleted aircraft. With help from a recovering pilot, Dr. White successfully lands the damaged plane in a desert. Following the emergency landing, Black Jack and Pinoko resume their travels on foot, having survived the dangerous ordeal.
7EP 7Black Jack Saves Aritani in Germany After Being Framed for Murder
May 29, 2006Black Jack and Pinoko visit a Middle Eastern town, befriending Japanese businessman Aritani. Black Jack is falsely arrested for murder, but Aritani provides an alibi. In gratitude, Jack offers free medical care. Aritani later returns to Germany, takes the blame for illegal fund transfers to an unknown group, and is hit by a train. Critical and dying, he is rushed to a German hospital. Lacking a license, Jack cannot operate until he convinces the hospital owner to let him buy the facility temporarily. He successfully saves Aritani’s life. Upon recovery, Aritani reveals the stolen money funded the Noir Project.
8EP 8Black Jack Investigates Non-Aging Coma Patient in England
Jun 5, 2006Black Jack travels to England to find Dr. Stein and encounters a man in a coma for 65 years who has not aged. While Dr. Stein seeks to study the patient for secrets of eternal youth, the niece hires Dr. Kiriko to end his life. Black Jack operates successfully, allowing the patient to wake up, but he rapidly ages and dies. Following this, Dr. Stein reveals he urged Dr. Honma to perform organ transplants on Black Jack 21 years ago after a severe explosion. As Dr. Stein succumbs to a condition known as "Phoenix disease," he provides Black Jack with the name of Dr. Jorujyu in New York, a former associate who might assist in his ongoing search.
9EP 9Black Jack travels to New York to assist Dr. Bart with a rare medical case.
Jun 12, 2006Black Jack and Pinoko journey to New York, where Dr. Bart requests assistance operating on his mother, Catherine Bart, who suffers from Honma's Hematoma. Jack recalls his mentor's warning against involvement with this condition and declines the request. The narrative references past events where the medical community accused Dr. Honma of conducting a live experiment on a patient with the rare disease, leading to his resignation. While searching for a clock found in an old group photograph, Jack is shot in the chest by Benitokage, a female assassin. After the attack, she receives orders to retrieve an item from Catherine Bart.
10EP 10Black Jack saves Catherine using a Type Hydra heart designed by his father Hazama Kagemitsu
Jun 26, 2006Black Jack survives an assassination attempt when his mother’s pendant deflects the bullet. He performs surgery on Dr. Bart’s mother, Catherine, discovering she possesses a Type Hydra artificial heart that continues beating after extraction. Jack replaces the device with another artificial heart to save her life. Investigation of Mio’s pendant reveals a microfiche showing the Type Hydra was designed by Jack’s father, Hazama Kagemitsu. Catherine explains that Kagemitsu abandoned her and the hospital for the Noir Project, but returned to save her life during a heart attack using the experimental device. Meanwhile, Benitokage steals the Type Hydra, leading to the cancellation of the order to kill Jack.
11EP 11Black Jack visits Dr. Jorujyu's Canadian cabin to treat his father's condition.
Jul 3, 2006Black Jack and Pinoko arrive at Dr. Jorujyu's lakeside cabin in Canada, where Jack is shot at by Yuri, who mistakes him for her brother. Dr. George is seriously ill, and Jack diagnoses mediastinal pneumonthorax, causing air to leak into a body cavity. Yuri's brother arrives, revealing himself as the infamous Dr. Kiriko, who plans to euthanize his father against Yuri's wishes after failing to save him. Dr. Kiriko explains that his father also suffers from the incurable Phoenix Disease, contracted during the Noir Project seeking eternal life. Jack successfully operates on Dr. Jorujyu, allowing him to temporarily regain consciousness, but he succumbs to the disease anyway. As Jack leaves, Yuri gives him the key to her father's research laboratory.
12EP 12Black Jack and Pinoco seek Dr. Jorujyu while Benitokage pursues them through a blizzard.
Jul 10, 2006Black Jack and Pinoco ride a train to locate Dr. Jorujyu's research facility, pursued by Benitokage and her henchman Souryu. After Benitokage tracks them through the snow and suffers injuries, Jack treats her wounds. Inside the cellar, Jack discovers a document regarding the mysterious Phoenix disease. As a blizzard intensifies, Benitokage regains consciousness, takes Pinoco hostage, and attempts to kill Jack before trying suicide. Jack intervenes again, but an avalanche destroys the cabin, causing the document to be lost. The trio hides in the cellar until Souryu rescues them. Benitokage then agrees to assist Jack, revealing that Dr. Kuma, identified from a group photograph, resides in the Gabonese Republic in Africa.
13EP 13Pinoko Returns to Japan with Sharaku Amidst Twin Brothers' Reunion
Jul 24, 2006Black Jack and Pinoko travel to Africa to find Dr. Kuma, where they meet Sharaku and his father. Concerned for Pinoko's safety, Jack asks Sharaku's father to send her back to Japan, causing her distress. While there, Pinoko encounters Al, now a grocery boy, and his twin brother Niko, who raises his adopted mother's deceased son, Johan, to give her hope. Al falls ill and requires an urgent liver transplant from a family member. Pinoko and Sharaku locate Niko, who agrees to donate despite fears of exposing his true identity to his adoptive mother. Ultimately, the situation resolves positively, leading to the reunion of the two brothers and their joint adoption by Niko's new parents.
14EP 14Black Jack and Pinoko investigate a mysterious disease in an African village while uncovering dark medical secrets.
Jul 31, 2006Black Jack and Pinoko reach a remote African village searching for Dr. Kuma, only to discover villagers dying from a condition linked to the Phoenix disease. After meeting a local girl named Mary, they locate Dr. Kuma, who saves Mary’s mother before Jack collapses from a tsetse fly bite. Dr. Kuma rescues Jack and reveals his past as Dr. Honma’s apprentice during the Noir Project, where Zen Mantoku gathered specialists to study eternal life. Dr. Jorujyu created the B.O.P. virus to power artificial organs, but experimental use on live subjects caused Dr. Honma to resign. When Dr. Kuma tested B.O.P. on animals, the results initially seemed promising until both the animals and villagers began dying. After Dr. Kuma is severely injured by a black panther while protecting Pinoko and Mary, the villagers donate blood to save him. Jack then receives urgent news that his father is in a coma.
15EP 15Black Jack faces his stepfather's plot to steal his mother's pendant while confronting his past.
Aug 15, 2006Black Jack returns to support his comatose father, but this visit is a trap orchestrated by Zen Mantoku, the father of his stepmother Renka. Mantoku seeks a pendant containing microfiche and kidnaps Pinoko to lure Jack. Benitokage intervenes to save them, but Jack is captured and brought before Mantoku. Mantoku reveals he caused the bomb explosion that killed Jack's mother and injured him, while forcing Kagemitsu into servitude. Jack refuses to join the organization, having already exposed the Noir Project secrets. He also identifies Benitokage as Kagemitsu's first daughter with Renka. After Benitokage helps Jack escape, he is shot in the leg. With Dr. Kuwata's assistance, Jack performs self-surgery using parts from his father's body. At the airport, a sniper targets Jack, but Benitokage sacrifices herself to save his life.
16EP 16Black Jack visits Sky Hospital to treat Zen Mantoku's Phoenix disease while Renka plots revenge.
Aug 29, 2006Black Jack prepares to return to Japan with Pinoko but is summoned to the Sky Hospital. There, he finds Zen Mantoku, the sole patient suffering from the Phoenix disease due to Noir Project B.O.P. injections. Jack agrees to help Dr. White create a cure for 1¥ billion. Meanwhile, Renka, bitter over losing her husband and daughter and resentful that Jack gave her her husband's ex-wife's face, secretly plots to kill Jack and steal the vaccine to profit from spreading the disease. During this tension, a henchman attempts to hijack the hospital, causing Mantoku to escape his containment capsule and release a mutated strain of the Phoenix disease aboard the aircraft.
17EP 17Black Jack races time to find a cure for the Phoenix disease while evading a nuclear missile.
Sep 4, 2006Black Jack redirects the Sky Hospital toward the North Pole as global doctors struggle against the Phoenix disease. Dr. Kuma warns that they have only 21 hours to find a cure before a nuclear missile destroys the virus and all infected individuals. Renka attempts to assassinate Jack but is stopped by her father, Zen Mantoku, resulting in both being shot. Zen dies, but Jack operates to save Renka, discovering an anti-virus in her system that can cure the disease. However, the missile has already been launched. As the disease spreads in Black Jack’s body, he faints and sees visions of Benitokage, Dr. Kiriko, Dr. Honma, his parents, and an adult 18-year-old Pinoko, who urges him to continue. Dr. White successfully evades the missile detonation, ensuring everyone’s safety. The cure, named Honma Antiserum after Dr. Honma, is made freely available. Black Jack and Pinoko return to the site of his ruined house to rebuild.
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Frequently asked questions
- How many episodes does Black Jack 21 have?
- Black Jack 21 has 17 episodes.
- When did Black Jack 21 come out?
- Black Jack 21 came out in 2006.
- Which studio made Black Jack 21?
- Black Jack 21 was produced by Tezuka Productions.
- Who directed Black Jack 21?
- Black Jack 21 was directed by Makoto Tezuka.
- Is Black Jack 21 finished?
- Current status of Black Jack 21: Finished.






